| 陆小玉，张美彪，向建平，杨水冰，杨井金，唐 维，杨娇娇，张 玲.怀化地区2型糖尿病慢性并发症临床特点分析.[J].中南医学科学杂志.,2015,43(6):658-661. |
| 怀化地区2型糖尿病慢性并发症临床特点分析 |
| The Clinical Characteristics in Type 2 Diabetic with Chronic Complication in Huaihua |
| 投稿时间：2015-07-06 |
| DOI： |
| 中文关键词: 2型糖尿病 慢性并发症 临床特点 |
| 英文关键词:Type 2 diabetes chronic complication clinical characteristics |
| 基金项目: |
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| 中文摘要: |
| 目的 分析怀化地区2型糖尿病（T2DM）住院患者糖尿病慢性并发症临床特点。方法 收集本科室住院1 033例2型糖尿病患者临床资料，登记其生活背景，以及实验室检查指标（血糖、血脂、胰岛素、24 h尿白蛋白）。根据国际临床分类法,眼底荧光造影，24 h尿白蛋白情况，神经肌电图，彩超检查，头部CT，心电图以及酶学诊断糖尿病视网膜病变、糖尿病肾脏病变、糖尿病周围神经病变、糖尿病大血管并发症，并进行对比分析。结果 就诊2型糖尿病患者女性年龄、糖尿病病程、高血压病史状况高于男性（P<0.05），女性高血脂、吸烟、喝酒患者较男性少（P0.005,0.000,0.000）。女性糖尿病视网膜病变及糖尿病周围神经病变患病率明显高于男性（P0.000,0.000）；糖尿病肾病的患病率则以男性多见（P0.038）。大血管病变患病率没有性别差异。结论 怀化地区糖尿病慢性并发症与年龄、糖尿病病程、肥胖、吸烟、血糖控制、高血压、高血脂有密切的关系；糖尿病慢性并发症存在明显的性别差异。 |
| 英文摘要: |
| Objective To investigate the clinical characteristics in patients with chronic complication of type 2 diabetes in Huaihua. Methods 1033 patients with T2DM were elected from the departmant of enducriology,the First People's Hospital of Huaihua from January 2012 to January 2013.Their living background was registered,as well as indexes about laboratory examination （blood glucose,blood lipid,blood insulin and 24 h urinary albumin）.Diabetic retinopathy,diabetic renal disease,diabetic peripheral neuropathy （DPN） and macrovascular complications in diabetes were diagnosed according to international clinical classification and 24 h urinary albumin,neural electromyologram （EMG）,CT of head,electrocardiogram and enzymological method. Result （1） Female patients compared with male patients in 1 033 patients diagnosed as T2DM,showed increase in age,the duration of diabetes,and hypertention （ P<0.05 ）But showed decrease in hyperlipidemia,smoking and drinking （ P0.005,0.000,0.000 ）（2） The female diabetic retinopathy and diabetic peripheral neuropathy prevalence were significantly higher than male （P0.000,0.000 ）,but the prevalence of diabetic nephropathy was lower than male （P0.038）（3） Macroangiopathy had no significant gender difference. Conclusion Age,duration of diabetes,obesity,smoking,blood glucose control,hypertension,hyperlipidemia are closely related to the T2DM diabetic microangiopathy.And this study showed the chronic complication of type 2 diabetes had different patterns in males and females. |
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