| 谢红萍，全 丽，黄 健，蒋 芬.539例肾活检病理临床分析.[J].中南医学科学杂志.,2015,43(4):414-417. |
| 539例肾活检病理临床分析 |
| The Pathologic Data Analysis of Renal Biopsy in 539 Cases |
| 投稿时间：2015-01-26 |
| DOI： |
| 中文关键词: 肾活检 回顾性分析 临床病理分型 |
| 英文关键词:renal biopsy retrospective analysis clinical pathological types |
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| 中文摘要: |
| 目的 探讨539例经皮肾活检的临床资料和病理类型之间的关系。 方法 回顾性收集539例经皮肾活检的临床病理资料，总结539例病例的临床特点和病理类型。 结果 539例肾活检组织中患者年龄13～66岁,平均32.6±13.2岁,男女之比1.12∶1.00。其中原发性肾小球疾病（PGD）422例（78.29%），继发性肾小球疾病（SGD）106例（19.67%），小管间质性疾病2例（0.37%），终末期肾脏疾病8例（1.48%）。PGD以IgA肾病居多（32.23%），其次分别为系膜增生性肾小球肾炎（27.01%）、微小病变（17.30%）、膜性肾病（14.22%）、局灶节段硬化性肾小球肾炎（5.92%）等。SGN中以狼疮性肾炎多见（52.83%），其次是乙肝病毒相关性肾炎（28.30%）、紫癜性肾炎（13.21%），本组还发现2例丙肝病毒相关性肾炎、1例重叠综合征及1例混合性结缔组织病。 结论 PGD仍是最常见的肾小球疾病，其中以IgA肾病和系膜增生性肾小球肾炎最常见；SGN检出中以狼疮性肾炎多见，女性发病率远高于男性，肝炎病毒相关性肾炎的检出率也明显增高。 |
| 英文摘要: |
| Objective To explore relationship between the clinical pathological date and pathological types of 539 cases of percutaneous renal biopsy. Methods The clinical pathologic data of 539 percutaneous renal biopsy cases from August 2005 to April 2014 were retrospectively analyzed,and the clinical feature and pathological type were summarized. Results The average age at renal biopsy was 32.6±13.2 （13～66） years old in 539 patients （male 285 and female 254,gender ratio was 1.12∶1）.422 cases （78.29%） were of primary glomerular disease and 106 cases （19.67%） were of secondary glomerular disease,2 cases（0.37%） were of tubular—interstitial disease，8 cases （1.48%） were of end-stagerenal disease.IgA nephropathy was the most patholigical type （32.23%） of PGD,followed by mesangial proliferative glomerulonephritis（27.01%）,minimalchangenephrosis （17.30%）,membranous nephropathy（14.22）,Focal stage sclerosing glomerulonephritis（5.92%）.Among secondary glomerular disease,the most type was lupus nephritis（52.83%）,followed by hepatitis B virus-associated glomerulonephritis（28.3%）,purpuric glomerulonephritis（13.21%）.Our group also found 2 cases of hepatitis C virus-associated glomerulonephritis,one case of overlap syndrome and one case of mixed connective tissue disease. Conclusion Primary glomerular disease is still the most common renal disease,and the most frequent pathological types of renal biopsy are mesangial proliferative glomerulonephritis and IgA nephropathy.Nearly nine years,SGD is increasing year by year,the most common is lupus nephritis.The incidence of female is much higher than male,hepatitis virus associated glomerulonephritis also increased obviously. |
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