刘艳敏,黄明志,罗俊彪.玉屏风散颗粒联合转移因子治疗儿童反复.[J].中南医学科学杂志.,2015,43(4):401-403.
玉屏风散颗粒联合转移因子治疗儿童反复
Observation of Efficacy of Yupingfeng Powder Combined Transfer Factor in Treatment of Recurrent Upper Respiratory Infection Patients
投稿时间:2015-05-05  
DOI:
中文关键词:  玉屏风  转移因子  儿童  反复上呼吸道感染
英文关键词:Yupingfeng Transfer Factor child recurrent upper respiratory infection
基金项目:衡阳市科技计划项目(2014KJ40).
作者单位
刘艳敏1,黄明志2,罗俊彪1* (1.广东省广州市黄埔区红十字会医院内科广东 广州5107602.广东省广州市天河区林和街社区卫生服务中心内科) 
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中文摘要:
      目的 观察玉屏风散颗粒联合转移因子治疗儿童反复上呼吸道感染(RURI)的疗效。 方法 采用随机分组法将64例入组患儿分成对照组、玉屏风组、转移因子组及联合治疗组,对照组10例,其他3组每组18例;对照组给予常规治疗,其他3组在常规治疗的基础上给予玉屏风散颗粒和/或转移因子胶囊治疗或联合治疗。比较各组患儿治疗期间各种症状、体征持续的时间;酶联免疫吸附试验(ELISA)检测患儿治疗前后血清中IgA、IgG及IgM水平,计数各组不良反应例数。 结果 转移因子组患儿咳嗽症状持续时间较玉屏风组短;联合治疗组患儿发热、咳嗽及肺内啰音持续时间均较玉屏风组、转移因子组短;转移因子组IgA水平治疗后较治疗前增加,联合治疗组治疗后IgA、IgG及IgM水平明显高于玉屏风组和转移因子组;对照组不良反应率最高,转移因子组最低,而联合治疗组较玉屏风组低。 结论 玉屏风联合转移因子治疗儿童反复上呼吸道感染具有可行性。
英文摘要:
      Objective To evaluate the effect of Yupingfeng powder combined Transfer Factor in treatment of recurrent upper respiratory infection (RURI) patients. Methods Samples were divided into 4 groups by randomized block method.The four groups were:control group,Yupingfeng Group,Transfer Factor group and combination group.The duration of symptoms and signs in each group was compared.The serum level of IgA,IgG and IgM before or after therapy was analyzed by enzyme linked immunosorbent assay (ELISA).The side effect rate was counted. Results During therapy,cough existed shorter in Transfer Factor group than in Yupingfeng group.The continued time of cough,fever and pulmonary rales was the shortest in combination group.The level of IgA was enhanced after therapy in Transfer Factor group.The serum level of IgA,IgG and IgM was the highest in combination group.The side effect rate in combination group was lower than the control group. Conclusion The combination of Yupingfeng and Transfer Factor in treating recurrent upper respiratory infection is feasible.
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