| 王 燕，曾高峰.右美托咪定在困难气道患者的应用.[J].中南医学科学杂志.,2015,43(3):308-310. |
| 右美托咪定在困难气道患者的应用 |
| Appliation of Dexmedetomidine in Difficult Airway Patients |
| 投稿时间：2014-11-11 |
| DOI： |
| 中文关键词: 右美托咪定 困难气道 麻醉诱导 呼吸抑制 气道梗塞 心血管反应 |
| 英文关键词:dexmedetomidine difficult airway anesthesia induction respiratory depression airway obstruction（awo） cardiovascular response |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨右美托咪定在困难气道患者麻醉诱导中的效果。 方法 回顾性分析困难气道患者60例，根据麻醉情况分为右美托咪定组、咪达唑仑组和异丙酚组，比较3组患者麻醉诱导过程中呼吸抑制、气道阻塞以及血压、心率、血氧饱和度的变化。 结果 右美托咪定组的呼吸抑制、气道阻塞明显低于其他两组（P＜0.05），血压、心率、血氧饱和度的波动也明显少于其他两组（P<0.05）。 结论 右美托咪定应用于困难气道患者的麻醉诱导可以显著降低呼吸抑制、气道阻塞的发生率，维持患者在诱导过程中血压、心率、血氧饱和度的平稳。 |
| 英文摘要: |
| Objective To analyze the clinical effects and the values about application of the dexmedetomidine in difficult airway patients during anesthesia induction. Methods 60 difficult airway patients were divided into group of dexmedetomidine （20 patients ）,group of midazolam （20 patients ） and group of propofol（20 patients ） in the second Affiliated Hospital from July 2011 to October 2013.We observed their respiratory depression,airway obstruction and the changes of blood pressure （BP）,heart rate （HR）,and blood oxygen saturation （BOS） during anesthesia induction. Results The rate of respiratory depression and airway obstruction is obviously less than medazolam group and propofol group.The changes of BP,HR,and blood oxygen saturation are less than the other groups.（P<0.05）. Conclusion Appling dexmedetomidine can obviously decrease the rate of respiratory depression and airway obstruction.It can also maintain BP,HR and blood oxygen saturation during anesthesia induction. |
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