| 符青云， 周春辉， 廖昆玲， 黄世章.Caveolin-1在复发膀胱尿路上皮癌组织中的表达及临床意义.[J].中南医学科学杂志.,2015,43(3):290-292. |
| Caveolin-1在复发膀胱尿路上皮癌组织中的表达及临床意义 |
| Expression and Clinical Significance of Caveolin-1 in Recurrent Bladder Cancer |
| 投稿时间：2015-02-17 |
| DOI： |
| 中文关键词: Caveolin-1 膀胱尿路上皮癌 复发 |
| 英文关键词:Caveolin-1 bladder cancer recurrent cancer |
| 基金项目: |
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| 中文摘要: |
| 目的 研究Caveolin-1在膀胱尿路上皮癌初发与复发之间表达的差异，探讨Caveolin-1与膀胱尿路上皮癌复发的分子机理及具有的临床病理意义。 方法 应用免疫组化方法检测23例初发膀胱尿路上皮癌和37例复发膀胱尿路上皮癌组织中Caveolin-1的表达，分析其与膀胱尿路上皮癌临床病理特征、肿瘤复发之间的关系。 |
| 英文摘要: |
| Objective To investigate the different expression of Caveolin-1 between primary and recurrent bladder cancer,explore its relationship with the molecular basis and clinical pathological characteristics of recurrent bladder cancer. Methods We examined the expression of Caveolin-1 in 23 cases with primary bladder cancer and 37 cases with recurrent bladder cancer by immunohistochemistry,and analyzed the relationship between molecular expression and tumor recurrence. Results Pathological characteristics were similar between the primary and the recurrent bladder cancer tissue.The expression of Caveolin-1 was significantly higher in the recurrent bladder cancer than that in the primary bladder cancer. Conclusion There was different expression of Caveolin-1 between primary bladder cancer and recurrent bladder cancer.Gene abnormality might be the molecular basis of recurrent bladder cancer. |
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