| 肖羚，蒋建军，刘列勇，张熠.冠心病介入治疗后伴发抑郁症的临床特点、治疗及预后.[J].中南医学科学杂志.,2014,42(6):605-608. |
| 冠心病介入治疗后伴发抑郁症的临床特点、治疗及预后 |
| The Cinical Characteristics,Treatment and Prognosis of Patients withDepression After Percutaneous Coronary Intervention |
| 投稿时间：2014-02-18 |
| DOI： |
| 中文关键词: 冠心病 经皮冠状动脉介入治疗 抑郁症 |
| 英文关键词:coronary artery disease percutaneous coronary intervention depression |
| 基金项目: |
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| 中文摘要: |
| 目的探讨冠心病经皮冠状动脉介入（PCI）术后伴发抑郁症的临床特点、治疗及预后。方法冠心病PCI术后213例患者，其中62例伴发抑郁症，从年龄、性别、文化程度、居住地、经济收入等临床特点及其常见的精神心理原因等方面作分析。将62例患者回顾性分成两组：综合治疗（药物+心理治疗）组31例，对照组(心理治疗组)31例。比较两组治疗后在抑郁评分、生存总质量、再住院率及主要心血管不良事件（MACE）发生率的变化。结果冠心病PCI术后伴发抑郁症，以文化程度越低、家庭经济条件越差（占46.2%）、病情越严重（心肌梗死占72.6%；二支、三支血管病变占79.0%）的患者居多。导致抑郁症的原因是多方面的，其中经济条件困难、负担过重（67.7%）、劳动力下降，无力担当家庭主力（51.6%）、担心冠心病再发（87.1%）是其主要原因。冠心病PCI术后伴发抑郁症的患者经药物和心理治疗后，患者抑郁评分、再住院率及MACE发生率下降，生存质量总分增高。综合治疗组效果优于对照组。结论冠心病患者PCI术后伴发抑郁症严重影响其短期和远期预后，加强药物和心理治疗（“双心治疗”）尤为必要。 |
| 英文摘要: |
| ObjectiveTo explore the cinical characteristics,treatment and prognosis of patients with depression after percutaneous coronary intervention（PCI）.MethodThere were 62 cases with depression among 213 cases after PCI analysed from the clinical characteristics and the common spirit of the psychological reasons such as age,gender,educational level,place of residence and income.The 62 cases were retrospectively assigned to the test group of drug and psychological therapy and control group of drug therapy,31 in each group.The changes in the two groups after treatment were compared using the depression scores,quality of life,rehospitalization rate and the incidence of major adverse cardiovascular events (MACE).ResultsThe patients after PCI with depression were more in those with the lower level of culture,the worse family economic condition (46.2%),the more serious condition (myocardial infarction accounted for 72.6%,the double-vessel disease ,triple-vessel disease accounted for 79.0%).The causes of depression are various and mainly related to the reasons including family financial difficulties,overburdening(67.7%),poor labor productivity and ability to bear family (51.6%) and fear of the recurrence of coronary heart disease (87.1%).Among the patients with depression after PCI,drug and psychological therapy can reduce the depression scores,the rehospitalization rate and the incidence of MACE and improve the quality of life.The efficacy of test groups was superior to control groups.ConclusionsThe short-term and long-term prognosis of patients after PCI with depression was seriously influenced.It is especially important to strengthen drug and psychological therapy (“double heart treatment ”). |
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