| 王霞，王湘屏，徐新.Bx亚型伴抗-B抗体产生的血型血清学特性分析与输血策略.[J].中南医学科学杂志.,2014,42(4):382-384. |
| Bx亚型伴抗-B抗体产生的血型血清学特性分析与输血策略 |
| The Characteristic of Blood Group Serologic and Blood Transfusion Strategy about Bx Subtypes with Anti-B |
| 投稿时间：2014-03-24 |
| DOI： |
| 中文关键词: ABO血型 Bx亚型 血型血清学 配合性输血 |
| 英文关键词:ABO blood group Bx subtypes blood group serologic transfusion |
| 基金项目: |
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| 中文摘要: |
| 目的分析Bx亚型伴抗-B抗体产生的血型血清学特性，并探讨其输血治疗方案。方法对ABO血型鉴定正反定型不符的样本进行吸收—放散试验、唾液血型物质凝集—抑制试验等血型血清学分析。对符合Bx亚型伴抗-B抗体产生血型血清学特性的患者，采取配合性血液输注，并观察输血疗效。结果血型血清学试验结果提示患者为Bx亚型伴抗-B产生，给予O型红细胞、AB型血浆、AB型血小板输注后，无输血不良反应，输血治疗效果良好。结论Bx亚型伴抗-B抗体产生的血型血清学特性由于B抗原表达减弱，在血型鉴定时导致正反定型不一致。与抗-AB凝集反应可增强，或不反应。H抗原表达强度与O细胞相似，同时产生低反应活性抗-B。分泌型个体唾液中可缺乏B物质，仅有H物质。此类患者在病情紧急，无法找到同型血液时，可采用配合性血液输注。 |
| 英文摘要: |
| ObjectiveThe study was desingned to analyze the characteristic of blood group serologic produced by Bx subtypes with anti-B,and explore the therapeutic schedule by blood transfusion.MethodsSamples of ABO blood group with identification of positive and negative stereotypes discrepancy were analyzed by blood type serological analysis such as absorb-radiation test,blood type material of saliva agglutination inhibition test.The patients accord with the characteristic of blood group serologic produced by Bx subtypes with anti-B were comparatively studied with blood transfusion treatment,and the curative effect of blood transfusion was observed.ResultsThe results of serological test suggested that the patients with blood type Bx subtypes and anti-B did not get a blood transfusion adverse reactions and has a good effect,when they received a blood transfusion therapy with O red blood cells,type AB blood platelets and plasma.ConclusionBecause B antigen expression decreased,serological characteristics of Bx subtypes with anti-B are inconsistent.The reaction with anti -AB agglutination can be enhanced or not react with the positive and negative blood type identification.The intensity of H antigen expression is similar to the O cells,while producing low reactivity of anti-B.The secreting type spittle can only have H,lack of B.The infusion treatment with assorted blood instead is safe and effective when the Bx subtypes with anti-B patients is in urgent circumstances and the same type of blood cannot be found. |
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