王霞,王湘屏,徐新.Bx亚型伴抗-B抗体产生的血型血清学特性分析与输血策略.[J].中南医学科学杂志.,2014,42(4):382-384.
Bx亚型伴抗-B抗体产生的血型血清学特性分析与输血策略
The Characteristic of Blood Group Serologic and Blood Transfusion Strategy about Bx Subtypes with Anti-B
投稿时间:2014-03-24  
DOI:
中文关键词:  ABO血型  Bx亚型  血型血清学  配合性输血
英文关键词:ABO blood group  Bx subtypes  blood group serologic  transfusion
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作者单位
王霞1,王湘屏2,徐新1 1.南华大学附属第二医院输血科湖南 衡阳 4210012.衡阳市中心血站质管科 
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中文摘要:
      目的分析Bx亚型伴抗-B抗体产生的血型血清学特性,并探讨其输血治疗方案。方法对ABO血型鉴定正反定型不符的样本进行吸收—放散试验、唾液血型物质凝集—抑制试验等血型血清学分析。对符合Bx亚型伴抗-B抗体产生血型血清学特性的患者,采取配合性血液输注,并观察输血疗效。结果血型血清学试验结果提示患者为Bx亚型伴抗-B产生,给予O型红细胞、AB型血浆、AB型血小板输注后,无输血不良反应,输血治疗效果良好。结论Bx亚型伴抗-B抗体产生的血型血清学特性由于B抗原表达减弱,在血型鉴定时导致正反定型不一致。与抗-AB凝集反应可增强,或不反应。H抗原表达强度与O细胞相似,同时产生低反应活性抗-B。分泌型个体唾液中可缺乏B物质,仅有H物质。此类患者在病情紧急,无法找到同型血液时,可采用配合性血液输注。
英文摘要:
      ObjectiveThe study was desingned to analyze the characteristic of blood group serologic produced by Bx subtypes with anti-B,and explore the therapeutic schedule by blood transfusion.MethodsSamples of ABO blood group with identification of positive and negative stereotypes discrepancy were analyzed by blood type serological analysis such as absorb-radiation test,blood type material of saliva agglutination inhibition test.The patients accord with the characteristic of blood group serologic produced by Bx subtypes with anti-B were comparatively studied with blood transfusion treatment,and the curative effect of blood transfusion was observed.ResultsThe results of serological test suggested that the patients with blood type Bx subtypes and anti-B did not get a blood transfusion adverse reactions and has a good effect,when they received a blood transfusion therapy with O red blood cells,type AB blood platelets and plasma.ConclusionBecause B antigen expression decreased,serological characteristics of Bx subtypes with anti-B are inconsistent.The reaction with anti -AB agglutination can be enhanced or not react with the positive and negative blood type identification.The intensity of H antigen expression is similar to the O cells,while producing low reactivity of anti-B.The secreting type spittle can only have H,lack of B.The infusion treatment with assorted blood instead is safe and effective when the Bx subtypes with anti-B patients is in urgent circumstances and the same type of blood cannot be found.
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