| 文兰，刘双全，谢小平.358株肺炎克雷伯菌的临床分布及耐药性分析.[J].中南医学科学杂志.,2013,41(1):78-79. |
| 358株肺炎克雷伯菌的临床分布及耐药性分析 |
| Clinical Distribution and Drug Resistance of 358 Strains of Klebsiella Pneumoniae |
| 投稿时间：2012-09-05 |
| DOI： |
| 中文关键词: 肺炎克雷伯菌 超广谱β-内酰胺酶 耐药性 |
| 英文关键词:klebsiella pneumoniae ESBLs drug resistance |
| 基金项目: |
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| 中文摘要: |
| 目的分析肺炎克雷伯菌的临床分布及耐药情况，为临床合理使用抗生素提供依据。方法采用回顾性调查的方法对358株肺炎克雷伯菌的标本来源及耐药性进行分析。结果358株肺炎克雷伯菌中，产ＥＳＢＬｓ阳性142株，阳性率为39.7％；ＥＳＢＬｓ阳性的肺炎克雷伯菌对所测抗菌药物耐药性显著高于产ＥＳＢＬｓ阴性菌，并且出现2株对亚胺培南耐药的肺炎克雷伯菌。结论产ＥＳＢＬｓ肺炎克雷伯菌在医院感染中十分流行，多重耐药明显。 |
| 英文摘要: |
| ObjectiveTo analyse the clinical distribution of Klebsiella pneumoniae and its drug resistance to provide the basis for rational clinical use of antibiotics.MethodsClinical distribution and antibiotic resistance of 358 strains of Klebsiella pneumoniae,isolated from various clinical samples,were retrospectively analyzed.ResultsIn 358 K.pneumoniae,the positive rate of ESBLs was 39.7% in 142 strains of ESBLs-producing K.pneumoniae;the drug resistance rate of ESBLs-producing K.pneumoniae was higher than that of non-ESBLs-producing strains.Moreover,there were two strains of imipenem resistant K.pneumoniae.ConclusionKlebsiella pneumoniae，producing ESBLs,might be prevalent in hospital,with significant multi-drug resistance. |
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