| 陈延群，孙建湘，彭超.康复新液联合复合维生素B防治含5-氟尿嘧啶化疗后口腔黏膜炎的疗效观察.[J].中南医学科学杂志.,2012,40(6):607-609. |
| 康复新液联合复合维生素B防治含5-氟尿嘧啶化疗后口腔黏膜炎的疗效观察 |
| Clinical Observation of Kangfuxin Joint Compound Vitamin B Tablets in Prevention of Oral Mucositis Induced by Chemotherapy Regimen of 5-Fluorouracil |
| 投稿时间：2012-03-16 |
| DOI： |
| 中文关键词: 康复新液 复合维生素B 5-氟尿嘧啶 化疗 口腔黏膜炎 疗效 |
| 英文关键词:Kangfuxin Compound Vitamin B 5-Fluorouracil chemotherapy oral mucositis effect |
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| 中文摘要: |
| 目的观察康复新液联合复合维生素B防治含5-氟尿嘧啶化疗后出现的口腔黏膜炎（oral mucositis，OM）的临床疗效。方法将60例接受含5-氟尿嘧啶化疗的患者回顾性分为治疗组与对照组。治疗组30例于开始化疗第一天配合使用康复新液联合复合维生素B治疗，连用2周；对照组30例于开始化疗第一天配合使用复合维生素B治疗，连用2周。观察疗效时间为治疗开始第一天至结束后。观察两组患者发生OM的分度情况和治疗效果。结果治疗组发生Ⅱ度以上OM的例数明显低于对照组（P<0.05）。治疗组疗效及有效率均明显高于对照组（P<0.05）。结论康复新液联合复合维生素B防治含5-氟尿嘧啶化疗后出现的OM具有明显疗效，能减轻化疗致OM的毒性反应。 |
| 英文摘要: |
| ObjectiveTo observe the clinical effect of Kangfuxin joint Compound Vitamin B tablets in prevention of oral mucositis induced by chemotherapy regimen of 5-Fluorouracil.MethodsSixty patients with chemotherapy regimen of 5-Fluorouracil were divided into treatment group and control group,with 30 in each group.Patients in treatment group were given Kangfuxin joint Compound Vitamin B tablets in addition to routine chemotherapy for two weeks,while the patients in control group were given Compound Vitamin B tablets only.ResultsThe control group showed more serious oral mucositis than the treatment group ；The total effective rate was 100% in treatment group and 80% in control group(P<0.05).ConclusionsKangfuxin joint Compound Vitamin B tablets in treating oral mucositis caused by chemotherapy regimen of 5-Fluorouracil proved to be more effective than the Compound Vitamin B tablets alone. |
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