| 叶祖峰，谢小武，张莲秀，姜湘华，毛辉.急性缺血性脑卒中患者尿酸和高敏C反应蛋白检测的临床意义.[J].中南医学科学杂志.,2012,40(6):591-593. |
| 急性缺血性脑卒中患者尿酸和高敏C反应蛋白检测的临床意义 |
| Clinical Significance of Uric Acid and High-Sensitivity C-Reactive Protein Determination in Patients with Acute Ischemic Stroke |
| 投稿时间：2012-01-28 |
| DOI： |
| 中文关键词: 急性缺血性脑卒中 尿酸 高敏C反应蛋白 |
| 英文关键词:acute ischemic stroke uric acid high-sensitivity C-reactive protein |
| 基金项目: |
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| 中文摘要: |
| 目的探讨急性缺血性脑卒中(AIS)患者血清中尿酸(UA)和高敏C反应蛋白(hs-CRP)水平变化的临床意义。方法AIS患者223例，其中大面积脑梗死组49例，非大面积脑梗死组174例，对照组240例，分别测定其UA和hs-CRP水平，并进行比较分析。结果AIS患者血清UA和hs-CRP水平较对照组均升高(P<0.05）；大面积脑梗死组UA和hs-CRP水平较非大面积脑梗死组和对照组明显升高(P<0.05)；非大面积脑梗死组较对照组UA(P>0.05)和hs-CRP(P<0.05）水平有所升高。结论血清UA和hs-CRP与AIS的发生有关，且hs-CRP水平能反映脑梗死的病变程度。 |
| 英文摘要: |
| ObjectiveTo explore the clinical significance of serum uric acid(UA) and high-sensitivity C-reactive protein(hs-CRP) in patients with acute ischemic stroke(AIS).MethodsTotal 223 cases of AIS were divided into 49 cases with large cerebral infarction and 174 cases with non-large cerebral infarction.240 cases were vecruited as the normal control group.The UA and hs-CRP level were detected and the results were analyzed statistically.ResultsThe UA and hs-CRP in AIS group were higher than those in the control group and the differences had statistical significance(P<0.05).Large cerebral infarction group was compared with non-large cerebral infarction group and normal control group,and the differences had statistical significance(P<0.05).Non-large cerebral infarction group was compared with normal control group,and the difference of UA had no statistical significance(P>0.05).The difference of hs-CRP had statistical significance(P<0.05).ConclusionThe UA and hs-CRP level are related with AIS and the hs-CRP level can reflect the degree of cerebral infarction. |
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