| 晏萍，陈君，雷文.老年高血压病患者动态血压参数与颈动脉粥样硬化的关系.[J].中南医学科学杂志.,2012,40(4):388-390. |
| 老年高血压病患者动态血压参数与颈动脉粥样硬化的关系 |
| The Relationship Between the Parameters of Ambulatory Blood Pressure and Carotid Artery Atherosclerosis in Old Hypertensive Patients |
| 投稿时间：2011-12-28 |
| DOI： |
| 中文关键词: 高血压病患者 老年 动态血压 颈动脉粥样硬化 |
| 英文关键词:hypertensive patients older ambulatory blood pressure carotid artery atherosclerosis |
| 基金项目: |
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| 中文摘要: |
| 目的探讨老年高血压病患者动态血压参数与颈动脉粥样硬化的关系。方法采用无创动态血压仪对185例老年高血压病患者进行24 h动态血压监测，根据检测结果将患者分为非勺型组(n=113)与勺型组(n=72)。同时采用彩色多普勒超声诊断仪测量患者颈动脉内膜－中膜厚度(IMT)，根据检测结果将患者分为IMT≤1.0 mm组(n=76)和IMT>1.0 mm组(n=109)。分析比较各组间临床及生物化学指标的差异。结果非勺型组和勺型组临床及生物化学指标比较，差异均无统计学意义(P>0.05)。非勺型组患者血压变异性（BPV）各项参数值与勺型组比较均有显著性增高(P﹤0.01)。非勺型组颈动脉粥样硬化的检出率(68.1%)显著高于勺型组(40.3%)(P<0.05)。IMT>1.0 mm组24 h动态血压变异性较IMT≤1.0 mm组明显升高(P<0.01)。结论 非勺型高血压病患者血压变异性较勺型高血压病患者大,且颈动脉内膜-中膜厚度增加者其血压变异性更为显著。 |
| 英文摘要: |
| ObjectiveTo investigate the relationship between the parameters of ambulatory blood pressure and carotid artery atherosclerosis in old hypertensive patients. Methods185 old hypertensive patients were divided into two groups: dipper group (n=72) and non-dipper group (n=113) according to results of the 24 h ambulatory blood pressure monitoring. Meanwhile all patients underwent ultrasound examinations of the heart and the IMT (intima-media thickness) of carotid arteries, and we classified them as carotid artery atherosclerosis group (n=109) or normal carotid artery group (n=76). ResultsThere were no significant differences in clinical manifestations and biochemical parameters between the dipper group and non-dipper group(P>0.05)． Compared with dipper group， non-dipper group presented obvious increase in each parameter values of ambulatory blood pressure variation(P﹤0.01). The detectable rate of CAS in non-dipper group (68.1%) was higher than that in dipper group (40.3%, P<0.05). The ambulatory pulse pressure in CAS group were significantly higher than that in CAN group (P<0.01). ConclusionCompared with dipper cases non - dipper cases have larger blood pressure variance， and the more blood pressure variance is in thickening IMT cases. |
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