| 谢海涛.结肠癌组织中miR-451表达的检测与分析.[J].中南医学科学杂志.,2012,40(3):257-259. |
| 结肠癌组织中miR-451表达的检测与分析 |
| Study on the Expression of MicroRNA-451 in Colon Cancer Tissues |
| 投稿时间：2011-10-20 |
| DOI： |
| 中文关键词: 结肠癌 miR-451 miRNA |
| 英文关键词:colon cancer miR-451 microRNA |
| 基金项目: |
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| 摘要点击次数: 938 |
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| 中文摘要: |
| 目的研究结肠癌组织和癌旁组织中miR-451的表达差异。方法分别使用miRNA芯片和Real-time PCR检测结肠癌组织和癌旁组织中miR-451。结果miRNA芯片检测发现结肠癌组织中miR-451相对于癌旁组织表达显著上调，并被Real-time PCR所证实。结论结肠癌组织中miR-451表达上调。 |
| 英文摘要: |
| ObjectiveTo study expression difference of microRNA-451 between colon cancer tissues and adjacent colon cancer tissues.MethodsThe expression level of miR-451 in colon cancer tissues and adjacent colon cancer tissues was detected by Chip-array and Real-time PCR differently.ResultsThe expression level of miR-451 was significantly up-regulated in colon cancer tissues comparing to adjacent colon cancer tissues and validated by Real-time PCR.ConclusionExpression level of miR-451 is up-regulated in colon cancer tissues. |
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