| 李高峰，李桂生，杨春旭，黄健，周建红.miRNA-9在食管癌细胞株中的表达.[J].中南医学科学杂志.,2012,40(2):136-138. |
| miRNA-9在食管癌细胞株中的表达 |
| MicroRNA-9 Expression and Clinical Significance in Esophageal Carcinoma Cells |
| 投稿时间：2011-10-13 |
| DOI： |
| 中文关键词: miRNA-9 食管癌细胞株 表达 |
| 英文关键词:miRNA-9 esophageal carcinoma cell expression |
| 基金项目:广西壮族自治区自然科学基金资助（0991269） |
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| 中文摘要: |
| 目的探讨miRNA-9在食管癌细胞株与正常食管上皮细胞的表达。方法采用荧光定量PCR法检测食管癌细胞株及正常食管上皮细胞miRNA-9基因的表达水平。结果5株食管癌细胞株和正常食管上皮细胞均存在miRNA-9基因表达，食管癌细胞株miRNA-9基因的表达量均高于正常食管上皮细胞(P<0.01)。结论 miRNA-9基因在食管癌细胞株表达明显上调，说明miRNA-9基因与食管癌的发生有关。 |
| 英文摘要: |
| ObjectiveTo explore the expression of miRNA-9 in human esophageal carcinoma cells and the normal esophageal epithelial cells.MethodsThe expression of miRNA-9 in human esophageal carcinoma cells and the normal esophageal epithelial cells were measured by fluorescent quantitation PCR.ResultsThe expression of miRNA-9 in five esophageal cancer cells and the normal esophageal epithelial cell were all detected，the expression of miRNA-9 in five esophageal cancer cells were higher than that in normal esophageal epithelial cells.ConclusionThe expression of miRNA-9 in esophageal carcinoma cells were markedly up-regulated,which suggested that the emerge of esophageal carcinoma was correlated with gene miRNA-9. |
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