| 刘珏，周建斌，张群锋.妊娠高血压疾病患者血流变学、凝血及D二聚体变化的临床意义.[J].中南医学科学杂志.,2011,39(5):541-543. |
| 妊娠高血压疾病患者血流变学、凝血及D二聚体变化的临床意义 |
| Clinical Significances of Hemorrheology，the Four Blood Coagulation Indexes in the Pregnancy Induced Hypertension |
| 投稿时间：2011-01-13 |
| DOI： |
| 中文关键词: 血流变学 凝血四项 D二聚体 妊娠期高血压疾病 |
| 英文关键词:hemorrheology four blood coagulation indexes D-dimers pregnancy induced hypertension |
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| 中文摘要: |
| 目的探讨妊娠期高血压疾病患者血流变学参数和凝血四项及D二聚体的变化特点。方法对49例妊娠期高血压疾病患者、56例正常妊娠妇女进行血流变学指标、凝血四项及D二聚体检测。结果妊娠期高血压疾病组的全血黏度、红细胞压积明显高于正常妊娠妇女（P<0.01）,妊娠期高血压疾病孕妇的凝血酶时间（PT）、活化部分凝血酶原时间（APTT）比正常孕妇明显缩短，而纤维蛋白原(FIB)的结果明显升高，血浆D二聚体水平明显高于正常妊娠妇女（P<0.01）结论监测孕妇血流变学和凝血四项及D二聚体指标，有助于预测妊娠高血征疾病，对妊娠高血压的治疗有一定的临床指导意义。 |
| 英文摘要: |
| ObjectiveTo explore changes of blood dynamics parameters、four blood coagulation indexes tests and D-dimers in normal pregnancy and pregnancy induced hypertension (PIH).MethodsThe subjects were divided into two groups,including normal pregnancy group (56) and PIH group (49).Indexs of Hemorrheology and the four blood coagulation indexes tests were carried out.Plasma levels of D-dimers were measured with enzyme linked immunosordent assays (ELISA ).Results Whole blood viscosity,hematocrit (HCT ) in PIH were obviously higher than those in normal pregnancy (P<0.01).The proth-rombin time（PT）and anginal partial thromboplastin time（APTT）of pregnant women with PIH was significantly shorter than normal pregnant women,but the level of fibrinogen（FIB）of pregnant women with PIH was significantly higher.Plasma D-dimers levels of PI H patients were higher than those of normal pregnant women (P<0.01).ConclusionMonitoring hemorrheology,the four blood coagulation and indexes D-dimers is conduced to predict outset of PIH.Furthermore,it could be helpful for treatment on PIH. |
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