| 唐健.醋酸氯己定栓剂的制备及质量控制.[J].中南医学科学杂志.,2011,39(2):227-229. |
| 醋酸氯己定栓剂的制备及质量控制 |
| Preparetion and Quality Control of Chlorhexidine Acetate Suppository |
| 投稿时间：2010-09-27 |
| DOI： |
| 中文关键词: 醋酸氯己定 制备 质量控制 |
| 英文关键词:chlorhexidine acetate preparetion quality control |
| 基金项目: |
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| 中文摘要: |
| 目的制备醋酸氯己定栓剂并建立其质量控制方法。方法以甘油和明胶为辅料，醋酸氯己定为主要成分制备栓剂，采用紫外分光光度法测定醋酸氯己定的含量。结果醋酸氯己定在2～10 μg/mL浓度范围内线性关系良好（r=0.999 6），平均回收率为99.6%，RSD=0.85%（n=9）。结论酸氯己定栓剂制备工艺可行，含量测定方法简便、准确可靠。 |
| 英文摘要: |
| ObjectiveTo prepare chlorhexidine acetate suppository and establish a method for quality control.MethodGelatin and glycerin were used as the vehicle,Chlorhexidine acetate suppository as main ingredient.The UV-spectrophotometry was used for quantitative analysis.ResultThe calibration curve of chlorhexidine acetate suppository was linear within a range of 2～10 μg/mL(r=0.999 6),the average recovery of chlorhexidine acetate suppository was 99.6%,RSD=0.86%(n=9).ConculsionThe chlorhexidine acetate suppository is feasible in technological process.The method of content determination is simple and accurate. |
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