| 任林,陈超群,张秋桂,谭波.尿路感染病原菌分布及耐药性分析.[J].中南医学科学杂志.,2010,(2):. |
| 尿路感染病原菌分布及耐药性分析 |
| The Distribution and Drug Resistance of Pathogenic Bacteria in Urinary Tract Infection |
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| DOI： |
| 中文关键词: 尿路感染 病原菌 耐药性 |
| 英文关键词:urinary tract infection pathogenic bacteria drug resistance |
| 基金项目: |
| 任林 陈超群 张秋桂 谭波 |
| 南华大学第一附属医院检验科;南华大学医学院微生物学与免疫学教研室; |
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| 中文摘要: |
| 目的了解医院近两年尿路感染病原菌菌群分布及其耐药情况。方法935份尿标本经培养检测,分离的致病菌用API鉴定系统进行菌株鉴定及药敏试验。结果共分离出197株病原菌,尿培养阳性率21.1%。革兰阴性菌构成比明显高于革兰阳性菌,最常见的尿路感染病原菌是大肠埃希菌(41.1%),其次是真菌(11.7%)、粪肠球菌(7.1%)、屎肠球菌(5.6%)和奇异变形杆菌(5.1%)。主要致病性革兰阴性杆菌对阿米卡星、乙酰西梭霉素、亚胺培南、美洛培南与阿莫西林/棒酸均敏感。主要致病革兰阴性菌(奇异变形杆菌除外)对替卡西林、阿莫西林、替卡西林/棒酸、头孢呋辛、环丙沙星、头孢西丁、头孢噻肟、哌拉西林、复方新诺明、庆大霉素、妥布霉素与头孢噻吩均耐药。葡萄球菌对米诺四环素、奎奴普丁/达福普汀、呋西地酸、替考拉宁、万古霉素、呋喃妥因与利福平敏感,而对青霉素、红霉素、四环素、复方新诺明及庆大霉素耐药,凝固酶阴性葡萄球菌(CNS)对多种抗生素耐药情况较金黄色葡萄球菌严重。肠球菌对多数常用抗生素耐药,仅对万古霉素敏感。结论尿路感染病原菌以条件致病菌为主,检出菌中除奇异变形杆菌外,均存在严重耐药问题,及时监测病原菌变化及耐药趋势以指导临床用药至... |
| 英文摘要: |
| Objective To investigate the distribution and drug resistance of pathogenic bacteria detected from the urinary tract infection during the last two years in our hospital. Methods We collected and analyzed 935 urinary tract infection samples.The API system was used to identify the pathogenic bacteria and conduct antibiotic susceptibility test. Results A total of 197 pathogenic bacteria were isolated.The positive rate was 21.1%.Gram-negative bacteria remained the more frequent pathogens than Gram-positive bact... |
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