| 万青松,李莉,谢红萍,欧继红,杨波.替米沙坦对2型糖尿病肾病患者蛋白尿的影响.[J].中南医学科学杂志.,2010,(1):. |
| 替米沙坦对2型糖尿病肾病患者蛋白尿的影响 |
| Effect of Proteinuria in Patients With Type 2 Diabetic Nephropathy by Telmisartan |
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| DOI： |
| 中文关键词: 替米沙坦 2型糖尿病肾病 洛沙坦 蛋白尿 |
| 英文关键词:telmisartan type 2 diabetic nephropathy losartan proteinuria |
| 基金项目: |
| 万青松 李莉 谢红萍 欧继红 杨波 |
| 南华大学第一附属医院肾内科;湖南环境生物职业技术学院护理学院; |
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| 中文摘要: |
| 目的探讨替米沙坦对2型糖尿病肾病患者蛋白尿的影响。方法36例2型糖尿病肾病患者,随机平均分为替米沙坦组和洛沙坦组,在常规药物治疗的基础上,分别予替米沙坦80 mg/天及洛沙坦100 mg/天治疗,测量患者血压、24 h尿蛋白定量及生化指标。结果30周后,两组患者血压、24 h尿蛋白定量均明显下降,而血糖、血脂、肾小球滤过率(GFR)无明显变化,替米沙坦组与洛沙坦组比较,24 h尿蛋白定量下降更显著,而血压下降差别不大。结论对于2型糖尿病肾病,替米沙坦比洛沙坦有更显著降尿蛋白的作用。 |
| 英文摘要: |
| Objective To investigate the effect of proteinuria of telmisartan on type 2 diabetic nephropathy. Methods In addition to ongoing treatment,thirty six type 2 diabetic patients with nephropathy were randomly devided into telmisartan group and losartan group,which were treated with telmisartan 80 mg once daily and losartan 100 mg once daily respectively,and blood pressure,24 h proteinuria and biochemical parameters were measured. Results After thirty weeks,24 h proteinuria and blood pressure decreased signific... |
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