| 曾希,曾颖,王承龙.33例鼻咽癌患者治疗前后血清EB病毒VCA-IgA跟踪分析.[J].中南医学科学杂志.,2010,(1):. |
| 33例鼻咽癌患者治疗前后血清EB病毒VCA-IgA跟踪分析 |
| The Follow-up Analysis of Serum EBV-VCA-IgA in 33 NPC Cases |
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| DOI： |
| 中文关键词: 鼻咽癌 EB病毒 EBV-VCA-IgA 跟踪分析 |
| 英文关键词:nasopharyngeal carcinoma epstein-barr virus EBV-VCA-IgA follow-up analysis |
| 基金项目: |
| 曾希 曾颖 王承龙 |
| 南华大学病理学教研室;南华大学护理学院;中南大学湘雅医院耳鼻喉科; |
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| 中文摘要: |
| 目的检测鼻咽癌患者临床过程中血清EB病毒VCA-IgA水平的变化情况,分析血清EB病毒VCA-IgA水平与鼻咽癌临床过程的相关性。方法使用酶联免疫吸附(ELISA)方法对33例鼻咽癌患者治疗过程中血清EB病毒VCA-IgA进行跟踪检测,结果采用SPSS13.0软件进行统计分析。结果治疗前,33例鼻咽癌患者中,血清EB病毒VCA-IgA阳性为19例(阳性率57.6%),第一个疗程后,阳性病例降至9例(阳性率36.4%),转阴率为36.8%。随着疗程进行,肿块减小,血清EB病毒VCA-IgA阳性率呈下降趋势。至跟踪的最后疗程,仍有4例阳性患者,但其抗体滴度较治疗前都有明显下降。经治疗,鼻咽癌患者血清EB病毒VCA-IgA阳性率较治疗前显著下降,滴度下降。结论血清EB病毒VCA-IgA抗体水平与治疗呈明显相关性,可作为鼻咽癌疗效判断及监测复发和评价预后的有效指标之一。 |
| 英文摘要: |
| Objective To investigate the relevance of serum EBV-VCA-IgA and clinical process in NPC. Methods The serum EBV-VCA-IgA was examined by ELISA in 33 cases with nasopharyngeal carcinoma(NPC) in the course of treatment.The results were statistically analyzed using SPSS13.0 software package. Results Before treatment,the positive rate of serum EBV-VCA-IgA in NPC was 57.6%(19 positive cases).After the first course of treatment,the positive rate of serum EBV-VCA-IgA reduced to 36.4%(9 positive cases).The darkening ... |
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