| 郭生豫,袁秀琴,冯伟,郭建波,徐丽丽,杨义.我国围产儿先天畸形危险因素的Meta分析.[J].中南医学科学杂志.,2010,(1):. |
| 我国围产儿先天畸形危险因素的Meta分析 |
| Meta-analysis of Risk Factors on Congenital Malformation in China |
| |
| DOI： |
| 中文关键词: 先天畸形 危险因素 Meta分析 |
| 英文关键词:meta-analysis congenital malformation risk factor |
| 基金项目: |
| 郭生豫 袁秀琴 冯伟 郭建波 徐丽丽 杨义 |
| 南华大学公共卫生学院流行病与统计学教研室;南华大学公共卫生学院卫生检验教研室; |
| 摘要点击次数: 724 |
| 全文下载次数: 0 |
| 中文摘要: |
| 目的探讨我国围产儿先天畸形发生的部分危险因素,为该病的防治提供重要线索。方法应用Meta分析方法对国内2000~2009年间发表的10篇关于先天畸形危险因素病例对照文献进行综合分析。结果孕期被动吸烟、出生缺陷家族遗传史、孕早期感染、流产史、孕早期服药、孕期接触污染、负性精神刺激、妊娠剧烈呕吐、孕期营养不良九个研究因素的合并OR及95%可信区间分别为2.820(1.490~5.332)、3.997(2.055~4.305)、5.225(2.679~10.190)、2.394(1.182~6.652)、3.130(1.902~5.153)、3.432(1.533~6.723)、1.707(1.305~2.232)、5.371(1.511~19.100)、3.911(3.449~4.441)。结论九个因素均为先天畸形发生的危险因素。 |
| 英文摘要: |
| Objective To evaluate the main risk factors on congenital malformation and to provid evidence for its prevention. Methods The results on the risk factors of birth defect from 2000~2009 were analyzed synthetically by Meta-analysis. Results The pooled OR values and 95%CI of smoking during pregnancy,family history of congenital defect,complications in early pregnancy,spontaneous abortion,medicine use in early pregnancy,exposure to damage chemicals in pregnancy,adverse mental stimulus,vomiting greatly during pr... |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|