| 王淑敏,罗祎敏.苏木水提取物对溃疡性结肠炎大鼠部分免疫功能的影响.[J].中南医学科学杂志.,2008,(4):. |
| 苏木水提取物对溃疡性结肠炎大鼠部分免疫功能的影响 |
| Immunomodulation of Aqueous Extract of Lignum Sappan on Ulcerative Colitis |
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| DOI： |
| 中文关键词: 苏木水提物 溃疡性结肠炎 免疫调节 |
| 英文关键词:haematoxylin Ulcerative colitis immunogenic regulation |
| 基金项目: |
| 王淑敏 罗祎敏 |
| [1]南华大学公共卫生学院,湖南衡阳421001 [2]南华大学肿瘤研究所,湖南衡阳421001 |
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| 中文摘要: |
| 目的 通过对溃疡性结肠炎大鼠(UC)的血清TIE亚群的检测和IgG、溶茵酶(LZM)含量的测定,探讨苏木对UC大鼠免疫功能的调节作用.方法 将Wistar大鼠随机分成6组,除正常时照组外,其余各组大鼠用免疫学方法制作实验UC模型.正常对照组和模型对照组每天灌服0.9%NaC1溶液2次,每次2 mL,药物组每天灌服苏木水提物药品液2次,每次2 mL,3周后处死后,检测各免疫指标.结果 苏木治疗组的CD4 /CD8 明显低于模型对照组,IgG的含量与模型组比较,12.5g/kg、25.0g/kg剂量组明显降低血清IgG水平,LSZ的含量也明显低于模型组,差异有显著性.治疗组胸腺指数和脾指数与模型组比较,差异无显著性.结论 苏木对UC大鼠的免疫功能有一定的调节作用. |
| 英文摘要: |
| Objective To explore the regulation effect of haematoxylin on immunogenic reaction of rats suffered from UC by serum TLC subgroup,IgG and lysozyme level examination.Methods The adults Wistar rats were randomly divided into six groups,the models of UC(except the normal group) have been made by immune methods.Normal group and UC group were administered 0.9% NaCl solution 2 mL(2 times a day).AELS groups were administered AELS solution 2 mL(2 times a day).These rats were killed after three weeks.All index were ... |
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