| 贺琳,杨天伦,李传昶,蒲晓群,郑昭芬.血清同型半胱氨酸对非糖尿病冠心病患者冠状动脉侧支循环的影响.[J].中南医学科学杂志.,2008,(3):. |
| 血清同型半胱氨酸对非糖尿病冠心病患者冠状动脉侧支循环的影响 |
| Effect of Serum Level of Homocysteine on the Development of Coronary Collateral Circulation in Non-diabetic Patients |
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| DOI： |
| 中文关键词: 冠状动脉侧支循环 非糖尿病 冠状动脉疾病 同型半胱氨酸 |
| 英文关键词:coronary collateral circulation non-diabetic coronary disease homocysteine |
| 基金项目: |
| 贺琳 杨天伦 李传昶 蒲晓群 郑昭芬 |
| [1]邵阳市中心医院心内科,湖南邵阳422000 [2]中南大学湘雅医院心内科,湖南邵阳422000 |
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| 中文摘要: |
| 目的 探讨非糖尿病患者血清同型半胱氨酸浓度与冠状动脉侧支循环形成的关系.方法 连续收集非糖尿病的冠心病患者63例,3支主要冠状动脉中至少有1支狭窄达90%以上,采用酶联免疫法测定其血清同型半胱氨酸浓度,按照Rentrop方法对冠状动脉侧支循环进行分级.结果 CCCO级组和CCC1级组血清同型半胱氨酸水平(13.28±2.85 μmol/L,12.19±2.61 μmol/L)明显高于CCC2级组和CCC3级组(11.10±2.25 μmol/L,8.92±1.23 μmol/L,P=0.000).按血清同型半胱氨酸浓度将患者分为正常浓度组和高浓度组2个亚组,高同型半胱氨酸血症患者在侧支形成不良组的分布高于侧支形成良好纽(P=0.029).结论 在严重冠状动脉狭窄病变的非糖尿病患者中,高同型半胱氨酸血症可能是冠状动脉侧支形成的一个不利因素. |
| 英文摘要: |
| Objective To investigate the relationship between serum level of homocysteine and the development of collaterals in non-diabetic patients with severe coronary artery stenosis. Methods 63 non-diabetic patients with at least one vessel's stenosis above 90 percents among three main vessels of coronary artery were consecutively enrolled into the study according to angiographic.The levels of serum homocystein were measured by ELISA method.Development of collaterals was classified by Rentrop's method. Results The... |
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