冯秀珍,沈沅.红外分光度法鉴别尼群地平片.[J].中南医学科学杂志.,2007,(4):606-607,619. |
红外分光度法鉴别尼群地平片 |
Identification of Nitrendipine Tablets by Infrared Spectrophoptometry |
投稿时间:2006-01-03 |
DOI: |
中文关键词: 尼群地平片 鉴别 红外分光光度法 红外分光度法 光谱鉴别方法 平片 Infrared Tablets Nitrendipine 快速 专属性 标准 谱集 红外光 药品 委员会 国家药典 完全 对照品 尼群地平 结果 红外吸收光谱 测定 |
英文关键词:nitrendipine Tablets identification infrared spectrophotometry |
基金项目: |
冯秀珍 沈沅 |
[1]常德市药品检验所,湖南常德415000 [2]南华大学生命科学院2002级药学班,湖南常德415000 |
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中文摘要: |
目的 建立尼群地平片红外光谱鉴别方法.方法 采用红外分光光度法,以三氯甲烷为溶剂提取、光谱纯溴化钾压片测定红外吸收光谱.结果 尼群地平片与尼群地平对照品的红外吸收光谱完全一致,并与国家药典委员会颁布的《药品红外光谱集》中的尼群地平的标准光谱一致.结论 本方法专属性好,可快速、准确地鉴别本品. |
英文摘要: |
Objective To establish a rapid and exclusive method for the identification of Nitrendipine Tablets. Methods The infrared spetrophotometry was adopted, in which the recrystallization was carried out with the Chloroform as the solvent and with spectral purity potassium bromide tabletting as the infrared absorption spectrum. Results The infrared absorption spectrum of the Nitrendipine Tablets was completely in confomaity with that of the control substance and the standard spectrum of Nitrendipine issued in Infrared Spectrum Album of Drugs by State Pharmacopoeia Committee. Conclusion This method is specific, fast and accurate, which can be used for the identification of Nitrendipine Tablets. |
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