| 黄丽芳,文锋,颜家运.环孢菌素A联合造血细胞因子治疗骨髓增生异常综合征的临床疗效.[J].中南医学科学杂志.,2007,(3):365-367. |
| 环孢菌素A联合造血细胞因子治疗骨髓增生异常综合征的临床疗效 |
| The Clinical Effect of Cyclosporin A Combined With Hematopoietic Growth5 Factor in Treatment of Patients With Myelodysplastic Syndrome |
| 投稿时间：2007-01-26 |
| DOI： |
| 中文关键词: 环孢菌素A 造血细胞因子 骨髓增生异常综合征 |
| 英文关键词:cyclosporinA hematopoietic wth factor myelodysplastic syndrome |
| 基金项目: |
| 黄丽芳 文锋 颜家运 |
| 南华大学第一附属医院血液科,湖南衡阳421001 |
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| 中文摘要: |
| 目的 探讨环孢菌素A(CsA)联合造血细胞因子治疗骨髓增生异常综合征(MDS)的临床疗效.方法 采用环孢菌素A(CsA)联合造血细胞因子治疗难治性贫血(MDS-RA)患者19例,定期观察患者外周血象和骨髓细胞形态学、并随诊观察远期疗效.结果 19例患者治疗后总有效率为73.7%(14/19),全部病例未见严重副作用,未发现向白血病转化的病例,治疗后骨髓细胞形态学未见改变.结论 环孢菌素A(CsA)联合造血细胞因子治疗MDS-RA疗效可靠. |
| 英文摘要: |
| Objective To explore clinical result of cyclosporinA(CsA) and hematopoietic growth factor for treatment of myelodysplastic syndrome(MDS) with refractory anemia(RA). Methods 19 cases of MDS-RA were treated with CsA and hematopoietic growth factor,while the changes of blood cells count,bone marrow and long-term therapy effect were observed.Result The total effective rate of 19 patients was 73.7%(8/19),no serious side effects occurred in all treated patients, the patients' anemia was improved and all transfusion-dependent patients achieved transfusion independence,the hematological of the bone marrow had no changes.Conclusion The treatment of MDS-RA by CsA combined with hematopoietic growth factor is effective. |
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