秦建平,陈荣安,张益康,李兴欢.性轴激素LH、FSH、T水平测定对Klinefelter''''s综合征的诊断意义.[J].中南医学科学杂志.,2005,(1):81-83.
性轴激素LH、FSH、T水平测定对Klinefelter''''s综合征的诊断意义
Serum Levels of Luinizing Hormone,Fouicle Stimulating Hormone and Testosterone:the Diagnosed Significance in Klinefelter''''s Syndrome
  修订日期:2004-11-05
DOI:
中文关键词:  Klinefelter综合征  特发性低促性腺激素性腺机能减退症  唯支持细胞综合征  特发性无精子症  特发性少精子症  性轴激素
英文关键词:klinefelter syndrome,idiopathic hypogonadotrapic hypogonadism,sertoli-cell-only syndrome,idiopathic azoospermia,idiopathic oligospermia,sex-hormone
基金项目:
秦建平  陈荣安  张益康  李兴欢
南华大学第一附属医院,湖南衡阳421001
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中文摘要:
      目的测定117例Klinefelter综合征(Klinefelter‘s syndrome ,KS),37例特发性低促性腺激素性腺机能减退症(idiopathic hypogonadotrapic hypogonadism,IHH),107例唯支持细胞综合征(sertoli-cell-only syndrome,SCOS),30例特发性无精子症(idiopathic azoospermia,IA),40例特发性少精子症(idiopathic oligospermia,IO)患者的性轴激素值,分析各疾病的LH、FSH、T值的差别,探索通过性轴激素测定诊断KS综合征的方法.方法应用放免分析法测定血清性轴激素水平;外周血淋巴细胞用1640培养基常规培养,制片,作染色体核型分析.结果通过测定血清LH、FSH、T值诊断KS,敏感性为94.87%,特异性为95.79%.结论性轴激素水平测定适合于基层医院对KS的诊断.
英文摘要:
      Objective To examine the sex-Hormones of 117 cases of Klinefelter syndrome,37 cases of idiopathic hypogonadotrapic hypogonadism,107 cases of sertoli-cell-only syndrome, 30 cases of idiopathic azoospermia and 40 cases of idiopathic oligospermia. To find a simpler way in diagnosis of Kelinefelter syndrome by statistically analyzing serum levels of luteinizing homone(LH),follicle-stimulating hormone(FSH) and Testosterone(T). Method The serum levels of LH,FSH and T were determined by radioimmunoassay(RIA). Blood lymphocyte was cultured for routing chromosome analysis. Result The sensitivity is 94.87%,specifity is 95.79% in Kelinefelter Syndrome diagnosis by serum LH,FSH,T examination. Conclusion Sex-hormone examination has significance in diagnosing klinefelter syndrome.
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