李艳军,段明,杨祚升.体外支原体药物敏感性的实验研究.[J].中南医学科学杂志.,2002,(2):135-137.
体外支原体药物敏感性的实验研究
Sensitivity Study of Mycoplasma to Antibiotics in Vitro
  修订日期:2001-11-22
DOI:
中文关键词:  体外支原体药物敏感性 实验研究 泌尿生殖道感染 抗生素
英文关键词:mycoplasma,urogenital tract infection,sensitivity to drug
基金项目:
李艳军  段明  杨祚升
南华大学第一附属医院 湖南衡阳421001 (李艳军,段明)
,南华大学第一附属医院 湖南衡阳421001(杨祚升)
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中文摘要:
      目的:比较常用抗生素对临床标本中泌尿生殖道支原体的抗菌作用。方法:采用液体培养法,对临床标本中168株解脲支原体(Uu)和51株人型支原体(Mh)对10种常用抗菌药物的敏感性进行测定。结果:168株Uu对强力霉素,美满霉素,环丙沙星,氧氟沙星,罗红霉素,白霉素,交水霉素,螺旋霉素,阿齐霉素,氯霉素的药敏率分别为36.3%,45.2%,85.7%,70.2%,84.5%,20.2%,20.2%,4.8%,54.8%,22.6%,51株Mh对强力霉素,美满霉素,环丙沙星,氧氟沙星,罗红霉素,白霉素,交沙霉素,螺旋霉素,阿齐霉素,氯霉素的药敏率分别为23.5%,43.1%,90.2%,64.7%,78.4%,15.7%,17.6%,9.8%,74.5%,43.1%,结论:加强以支原体药敏测定,对指导临床治疗有重要意义。
英文摘要:
      Objective: To compare the effect of antibiotics on urogenital mycoplasma from clinical spceimens.Methods: The susecptibi1ity of 168 strains of ureaplasma uiealyitcym (Uu) and 51 strains of mycoplasma hominis (Mh) from clinical specimens were determined using tube culture method in vitro. Results: For 168 Uu the percentage of susceptible strains (R) was as follows: doxycyclin (36.3%) ,minocycline(45.2%) , ciprofi1oxacin (85.7%), ofloxacin (70.2%), roxithromycin (84.5%), leucomycin (20.2%), josamycin (20.2%), acetyl- spiramycin (4.8%), azithromycin (54.8%), chloromycetin (22.6%) respectively. For 51 Mh the percentage of susceptible strains (R) was as follows: doxycyclin (23.5%), minocycline (43.1%) ,ciprofiloxacin (90.2%) ,ofloxacin (64.7%) ,roxithromycin (78.4%), leucomycin (15.7%), josamycin(17.6%), acetyl-spiramycin (9.8%), azithromycin (74.5%), chloromycetin ( 43.1 %)respectively. The strains of resistance to antibiotics in both Uu and Mh were existed. Conclusion: The susceptibility monitoring of urogenital mycoplasma has important significance in clinical drug treatment.
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