| 张恺芳,陈超男,高治平,贺毅.缺血预处理对家兔缺血再灌注心肌血流动力学的影响.[J].中南医学科学杂志.,2001,(3):235-236. |
| 缺血预处理对家兔缺血再灌注心肌血流动力学的影响 |
| Effects of Ischemic Preconditioning on Cardiac Hemodynamics during Myocardiac Ischemic-reperfusion in Rabbits |
| 修订日期：2000-11-21 |
| DOI： |
| 中文关键词: 缺血预处理,缺血/再灌注,血流动力学,心肌保护 |
| 英文关键词:ischemic preconditioning,ischemia/reperfusion,hemodynamics,cardioprotection |
| 基金项目: |
| 张恺芳 陈超男 高治平 贺毅 |
| 南华大学基础医学院生理学教研室!湖南衡阳421001 |
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| 中文摘要: |
| 目的 探讨缺血预处理对兔缺血再灌注心肌血流动力学的影响。方法 采用BL - 310多通道记录系统处理对照组、缺血再灌注组和缺血预处理组在不同时点兔血流动力学的有关指标。结果 结扎兔冠状动脉左室支 30min ,再灌注 2 0min ,左室收缩及舒张功能呈进行性下降 ;结扎前行缺血预处理可减轻左室收缩和舒张功能的降低。结论 缺血预处理对缺血再灌注损伤时兔左室功能具有保护作用 |
| 英文摘要: |
| To study the effects of ischemic preconditioning(IP) on cardiac hemodynamics in rabbits,an ischemic-reperfusion model of rabbit was used.BL-310 Multichannel Recording System was used to process some indicators of cardiac hemodynamics in rabbits in different time.The results showed that left venticular systolic function and left venticular diastolic compliance progressively decreased during 30 min of ischemia and 20 min of reperfusion.The ischemic preconditioning before ischemia could inhibit the decrease of left venticular systolic function and left venticular diastolic compliance.The results indicated that IP has a protective effect on left venticular function in ischemia reperfused rabbits. |
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