| 肖钢明.先天性心脏病患者血浆内皮素与内源性类洋地黄素水平测定及其意义.[J].中南医学科学杂志.,2000,(4):. |
| 先天性心脏病患者血浆内皮素与内源性类洋地黄素水平测定及其意义 |
| Significance and Concentrations of Plasma Endothelin and Endogenous Digitalis-like Factor in Patients with Congenital Heart Disease |
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| DOI： |
| 中文关键词: 内皮素,内源性类洋地黄素,先天性心脏病 |
| 英文关键词:endothelin,endogenous digitalis-like factor,congenital heart disease |
| 基金项目: |
| 肖钢明 |
| 深圳市南山区人民医院儿科!广东深圳518052 |
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| 中文摘要: |
| 应用放射免疫方法测定 2 4例先天性心脏病 (CHD)患者血浆内皮素 - 1(ET - 1)及内源性类洋地黄素 (EDLF)水平。结果显示 :血浆ET - 1水平CHD组明显高于正常对照组 (P <0 .0 1) ,CHD -LR组明显高于CHD -RL组 (P <0 .0 1) ;血浆EDLF水平CHD组明显低于正常对照组 (P <0 .0 1) ,CHD -LR组略高于CHD -RL组 (P >0 .0 5)。提示ET - 1及EDLF在CHD的病理生理过程中起一定作用 |
| 英文摘要: |
| Concentrationsofendothelin - 1(ET - 1)andendogenousdigitatislikefactor (EDLF)intheplasmain 2 4patientswithcon genitalheartdisease(CHD) ,amongofthem ,16patientswithCHDofthelefttorightshunt(CHD -LR) ,8patientswithCHDoftherighttoleft (CHD -RL) ,weremeasuredbyradioimmunoassay.TheresultsshowedthattheplasmalevelofET - 1inpatientswithCHDwerehigherthan thatin 12normalchildren (P <0 .0 1)andthatinpatientswithCHD -LRwerehigherthanthatinpatientswithCHD -RL(P <0 .0 1) ;the plasmalevelofEDLFinpatientswithCHDwerelessthanthatin 12normalchildren (P <0 .0 1) .TheresultsshowthatET - 1andEDLFmay playacertainroleinthepathogenesisofCHD . |
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