| 戴爱国,范咏梅,李柏完,陈红芳,肖秋元.降逆汤对支气管哮喘并胃食道返流患者肺功能及气道反应性的影响.[J].中南医学科学杂志.,1999,(3):. |
| 降逆汤对支气管哮喘并胃食道返流患者肺功能及气道反应性的影响 |
| Effect of Jiangni Decoction on Pulmonary Function and Airway Responsiveness in Asthmatics with Associated Gastroesophageal Reflux |
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| DOI： |
| 中文关键词: 降逆汤,哮喘,胃食道返流,气道反应性 |
| 英文关键词:Jiangni Decoction,asthma,gastroesophageal reflux,airway responsiveness |
| 基金项目: |
| 戴爱国 范咏梅 李柏完 陈红芳 肖秋元 |
衡阳医学院第三附属医院(戴爱国，李柏完，肖秋元)
，衡阳医学院第一附属医院(范咏梅，陈红芳)
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| 中文摘要: |
| 为探讨降逆汤对支气管哮喘（ 简称哮喘） 并胃食道返流（ Ｇ Ｅ Ｒ） 患者肺功能与气道反应性的影响，本研究将５４ 例哮喘并 Ｇ Ｅ Ｒ 患者随机分为降逆汤组、西药组与对照组，前两组分别给予降逆汤与雷尼替丁等西药治疗６ 周。结果显示：降逆汤治疗后患者哮喘与 Ｇ Ｅ Ｒ 临床积分明显降低，内窥镜下食管炎明显改善，肺功能指标显著增加，气道反应性则明显降低（ Ｐ 均＜ ０ ．０１） ；且和对照组比较，差异有非常显著性（ Ｐ 均＜ ０ ．０１） ，但与西药组比较，差异无统计学意义（ Ｐ 均＞ ０ ．０５） 。提示降逆汤通过治疗 Ｇ Ｅ Ｒ 而改善哮喘并 Ｇ Ｅ Ｒ患者之肺功能与气道反应性。 |
| 英文摘要: |
| To study the effects of Jiangni Decoction on pulmonary function as well as airway responsiveness in asthmatics with associated gastroesophageal reflx(GER),54 patients with asthma and GER were divided into 3 groups randomly:Jiangni Decoction group(n=18),western drugs group(n=18) and control group(n=18). In the Jiangni Decoction and western drugs groups,patients were administered with Jiangni Decoction and Ranitidine as well as Cisapride for 6 weeks,respectively.The results showed that the refluent and asthmatic symptoms were significantly relieved and the VC,VC% Pred,FVC,FVC% Pred,FEV 1,FEV 1/FVC,PEF,PEF% Pred,histamine PC 20 FEV1 were markedly increased after Jiangni Decoction antireflux treatment(P<0.01).There were significant differences in these indexes between Jiangni Decocation group and control group(P<0.01),but no difference between Jiangni Decoction group and western drugs group(P> 0.05) .These results indicate that the pulmonary function and airway responsiveness can be improved after Jiangni Decoction antireflux treatment in asthmatics with associated GER. |
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