| 廖力夫,何玉媛,刘传湘,李贵荣,袁亚莉.过亚硝酸根分解反应机制的光度法研究.[J].中南医学科学杂志.,1996,(4):. |
| 过亚硝酸根分解反应机制的光度法研究 |
| Spectrophotometric Studies on The Decomposition of Peroxynitrite |
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| DOI： |
| 中文关键词: 过亚硝酸根，分解，羟自由基，分光光度法 |
| 英文关键词:peroxynitrite,decomposition,free hydroxyl radical,spectrophotometry, |
| 基金项目: |
| 廖力夫 何玉媛 刘传湘 李贵荣 袁亚莉 |
| 衡阳医学院基础化学教研室 |
| 摘要点击次数: 799 |
| 全文下载次数: 1 |
| 中文摘要: |
| 以亚甲蓝和苯甲酸为羟自由基捕获剂，用分光光度法研究了过亚硝酸根分解反应的机制。研究发现过亚硝酸根在生理ｐＨＴ分解时有羟自由基与亚甲蓝和苯甲酸的加合物产生。亚甲蓝和乙醇不影响过亚硝酸根的分解速率。羟自由基加合物生成速率对过亚硝酸根浓度为一级，对捕获剂浓度接近为零级。表明过亚硝酸根在生理ｐＨ下分解时有羟自由基产生。 |
| 英文摘要: |
| The mechanism of peroxynitrite decomposition was invastigated by spectrophotometry with methylene blue and benzoic acid as hydroxyl radical trappers.It was found that the adducts of hydroxyl radical with either methylene blue or benzoic acid were produced in the decomposition of peroxynitrite at physiological pH.The rate of decomposition was not affected by methylene blue and ethanol.The rate of formation of adducts was one order to the concentration of peroxynitrite and Zero order to the concentration of trappers.The results indicated that the decomposition of peroxynitrite at physiological pH produces free hydroxyl radical. |
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