| 廖瑛,田英,曹盛俊,李春,彭辉.碘化胶原的研制及杀菌效果的初步观察.[J].中南医学科学杂志.,1996,(2):. |
| 碘化胶原的研制及杀菌效果的初步观察 |
| Preparation of Collagen-Polyvinylpyrrolidone-Iodineand Observation of Its Germicidal Efficacy |
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| DOI： |
| 中文关键词: 衡阳医学院第一附属医院骨科胶原 聚乙烯吡咯烷酮 碘 稳定性 杀菌效果 |
| 英文关键词:Collagen,Polyvinylpyrrolidone,Iodine,Stability,Germicidal efficacy |
| 基金项目: |
| 廖瑛 田英 曹盛俊 李春 彭辉 |
| 衡阳医学院生化教研室 |
| 摘要点击次数: 849 |
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| 中文摘要: |
| 本文应用胶原、聚乙烯吡咯烷酮作为碘的载体，制成胶原－聚乙烯吡咯烷酮－碘，一种治疗骨髓炎的植入式缓释体，并在室温保存条件下对其稳定性及存放１８０ｄ后的杀菌效果进行了观察。结果表明：在室温下，碘化胶原存放１８０ｄ后，有效碘仅下降０．６６％，此时对金黄色葡萄球菌、大肠杆菌、绿脓杆菌具有较强的杀灭能力。 |
| 英文摘要: |
| Collagen - Polyvinylpyrrolidone-Iodine(C-PVP-I) was prepared and its stability and germicidal efficacy was observed.The results indicated that the decrease rate of available iodine was 0.66%after storage for 180 days at room temperature.A solution of the C-PVP-I contaning 12.5mg/Lavailable indine with 5 min Contact time could kill 100% of staphylococcus aureus, Escherichia Coli and Pseudomonas aeruginosa.When 20 % Calf serum was added to the bacterial suspension,the germicidal efficacy decreased. |
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