戴爱国,梁永康,刘启良,蒋宁一,梁九根.核素显象在慢性支气管炎、支气管哮喘并胃食道返流中的应用.[J].中南医学科学杂志.,1994,(2):.
核素显象在慢性支气管炎、支气管哮喘并胃食道返流中的应用
Application of radionuclide gastroesophageal reflux imaging in patients with chronic bronchitis and asthma
  
DOI:
中文关键词:  支气管炎,哮喘,胃食道返流,放射性核素成象
英文关键词:bronchitis,asthma,gastroesophageal reflux,radionuclide imaging
基金项目:
戴爱国  梁永康  刘启良  蒋宁一  梁九根
中山医科大学孙逸仙纪念医院,同济医科大学
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中文摘要:
      为探讨慢性支气管炎(慢支)、支气管哮喘(哮喘)与胃食道返流(GER)的关系,我们采用放射性核素显象对29例慢支、32例哮喘患者及9例正常对照者进行研究。结果:慢支组和哮喘组并发GER的发生率分别为5l.74%和37.50%,而对照组未发现GER;胃食道核素显象诊断GER的敏感性为100%,特异性为68.42%,诊断正确率为80%;慢支、哮喘并发GER者与其无GER者之间肺通气功能值差异无显著性(P>0.05);肺核素显象未发现肺吸入返流物现象。提示:慢支和哮喘患者伴有较高的GER发生率,从而推测慢支、哮喘与GER之间有密切的关系。
英文摘要:
      To determine the reltionship between gastroesophageal reflux(GER)and pulmonary diseases,we studied 29 chronic bronchitics,32 asthmatics,and 9 control subjects,GER was diagnosed by esophageal endoscopy and biopsy and gastroesophageal scintiscanning.Frequency of GER in the chronic bronchitics was 5l.74%;In the asthmatics it was 37.5%;no GER was confirmed in the control subjects.Gastroesophageal scintisean had l00%sensitivity,but only 68.42%specificity. pulmonary function tests did not show any differences between patients with or without relux(P>0.05).The mechanism whereby reflux triggers pulmonary problems was investigated by using the scintiscan for pulmonary aspiration,but no pulmonary aspiration was detected.Thus,our results show that GER is frequent in chronic bronchitics and asthmatics.which indicates that there is closely relationship between GER and chronic bronchitis as well as asthma.
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