陈国强,张彤,杨永宗.内毒素刺激猪主动脉内皮细胞PGI_2生成.[J].中南医学科学杂志.,1991,(3):.
内毒素刺激猪主动脉内皮细胞PGI_2生成
Endotoxin Stimulated Cultured Pig Aortic Endothelial Cells to Produce Prostacyclin
  
DOI:
中文关键词:  内毒素,内皮细胞,前列环素
英文关键词:Endotoxin,Endothelial cell,PGI_2
基金项目:
陈国强  张彤  杨永宗
衡阳医学院病理生理教研室,衡阳医学院病理生理教研室,衡阳医学院病理生理教研室
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中文摘要:
      本文初步观察了 E Coli 内毒素对体外培养的猪主动脉内皮细胞 PGI_2生成的影响。结果发现内毒素显著刺激培养细胞 PGI_2的生成,并呈剂量(1—1000ng/ml)和时间(6—24小时)依赖性,但不同于其它刺激剂,内毒素的作用时间至少需要2小时以上。
英文摘要:
      The effcts of E Coli endotoxin PGI_2generation of cultured pig aortic endothelial cells were observed.The result showed endotoxin does dependently (1ng/ml-1ug/ml)and time depen- dently(6-24h)stimulated the generation of large amounts of PGI_2in cultured cell.
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