| 杨永宗,涂玉林,刘德平.高脂血症损伤动脉内膜的实验研究 Ⅲ、血小板丙二醛含量的变化.[J].中南医学科学杂志.,1986,(1):. |
| 高脂血症损伤动脉内膜的实验研究 Ⅲ、血小板丙二醛含量的变化 |
| EFFECT OF HYPERLIPEMIC SERUM ON MALONDIALDEHYDE CONTENTS OF THE RABBIT PLATELETS |
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| DOI： |
| 中文关键词: 前列腺素,丙二醛,硫代巴比妥反应,高脂血症,血小板,动脉内膜损伤 |
| 英文关键词:prostaglandin malondialdehyde(MDA) hypercholesterolemia platelet aortic intima injury |
| 基金项目: |
| 杨永宗 涂玉林 刘德平 |
| 衡阳医学院心血管病研究室，衡阳医学院心血管病研究室，衡阳医学院心血管病研究室 |
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| 中文摘要: |
| 本文报告静脉注射高脂血清后兔血小板丙二醛含量的变化。结果表明,注射高脂血清后3小时和6小时,血小板丙二醛均显著增加。与对照组比较,注射高脂血清6小时,血小板丙二醛的增加具有非常显著的差异。文章简要讨论了丙二醛增加的意义,联系我们早年的工作,推测高脂血清损伤动脉内膜的过程,系通过影响血小板功能和前列腺素代谢而起作用。 |
| 英文摘要: |
| In order to investigate the effects of hyperlipemia on prostaglandins metabolism of platelets, malondialdehyde(MDA) contents of the rabbit platelets were measured at the third and sixth hour after giving single intravenous injection of hyperlipemic serum. The results showed that MDA contents of the platelets increased significantly after injection of hyperlipemic serum. Again, in the control group of rabbits, no remarkable changes were noted at the third and sixth hour after the injection of equal amount of normal serum. The significance of MDA content which increased in the platelets in endothelial injury by hyperlipemia was discussed. |
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