高仕瑛,欧阳敦惜,王湘伟.氨熏蒸降解稻谷中黄曲霉毒素B_1的安全性毒理学试验.[J].中南医学科学杂志.,1985,(3):.
氨熏蒸降解稻谷中黄曲霉毒素B_1的安全性毒理学试验
  
DOI:
中文关键词:  稻谷,气态氨熏蒸,黄曲霉毒素B_1,食品安全性毒理学评价
英文关键词:Rice Ammonia fumigation Aflatoxin B1 The toxicologic evaluation procedures for the safe use of food
基金项目:
高仕瑛  欧阳敦惜  王湘伟
衡阳医学院微生物学教研室,衡阳市卫生防疫站,衡阳市粮食局
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中文摘要:
      在薄层层析法确定氨熏蒸可降解稻谷中所含黄曲霉毒素B_1的基础上,按我国现行的《食品安全性毒理学评价程序》、对经氨熏蒸、毒素降解后的稻谷(或加工成的大米)的卫生品质进行了评价。按规定我们完成了评价程序的第一阶段(急性毒性与七日喂养)、第二阶段(致畸、致突变的三个试验)及第三阶段(亚慢性毒性)试验。全部结果证实,氨熏蒸可有效地降解稻谷中黄曲霉毒素B_1,并且未发现其降解物对实验动物有毒性。认为此去毒法可在有关部门推广应用。
英文摘要:
      The method of thin-layer chromatography proved that, aflatoxin B1 presented in rice can be decomposed by ammonia fumigation. On the basis of the above experiment, we evaluated the sanitary quality of rice, unhusked and processed, after gaseous ammonia fumigation according to "The toxicologic evaluation procedures for the safe use of food". According to the regulation, we carried out the evaluating procedure in three stages'. The first stage was the stage of acute toxicity and the seven-day feeding test. The second stage included three tests for aberration and mutagenicity and the third stage, the stage of sub-chronic toxic test. All the results verilied that fumigation of unhusked rice by ammonia may cause effective decompostion of aflatoxin B1 in rice. The decomposition products produced no toxic effect on experimented animals. For this reason we recommend the general application of the method in the process of detoxification of grains.
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